Back to results
US 2013/0295044 A1Published application
Natural killer cells with enhanced immune response
AssigneeBoard of Trustees of Michigan State University
InventorsSungjin Kim, Jeannine Scott
Life of this patent
Estimating the term…
Abstract
The invention relates to a specialized subpopulation of natural killer cells that have enhanced effector functions and the potential to kill malignant tumor cells or infected cells when the natural killer cells are exposed to an antibody bound to the tumor cells or the infected cells.
Claims23
A composition comprising natural killer cells that do not express substantial FcRγ (g−NK cells).
The method of any of statements 9-11, wherein a cell receptor is activated in the g−NK cells upon contact with an antibody.
A method of identifying g−NK cells comprising:
- identifying a subset of natural killer cells in a population of lymphocytes that do not express substantial FcRγ to thereby identify g−NK cells.
Dependencies are inferred from the claim text.