Salts of benzimidazole compound and use thereof
AssigneeTakeda Pharmaceutical Company Limited
InventorsKeiji KAMIYAMA, Hideo HASHIMOTO
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Abstract
A sodium salt, magnesium salt, lithium salt, potassium salt, calcium salt or barium salt of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole, and a pharmaceutical composition comprising the salt. The novel salt is useful as an excellent antiulcer agent.
Claims3
1-13. (canceled)
A crystal solvated with isopropyl alcohol of sodium salt of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole, wherein the X-ray diffraction spectrum have the following diffraction peaks:
- 16.00, 12.65, 7.98, 7.51, 6.35, 5.09, 4.99, 4.92, 4.82, and 4.21 Angstrom.
A crystal of sodium salt of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole Monohydrate, wherein the X-ray diffraction spectrum have the following diffraction peaks:
- (iii) 8.89, 8.47, 5.64, 5.24, 4.84, 4.23, 4.20, 4.09, 3.60, and 3.36 Angstrom.
Dependencies are inferred from the claim text.