Use in brain degenerative diseases
OwnerVolker Brinkmann, Nicole Kaneider +1inventors
InventorsVolker Brinkmann, Nicole Kaneider, Christian J. Wiedermann
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Abstract
Disclosed is a new use for sphingosine-1-phosphate (S1P) receptor agonists in the treatment of progressive dementia or brain degenerative diseases.
Claims7
A pharmaceutical composition for use in treating progressive dementia or brain degeneration, β-amyloid-related inflammatory diseases or disorders or for reducing or inhibiting loss of cognitive abilities comprising a sphingosine-1-phosphate (S1P) receptor agonist or a pharmaceutically acceptable salt thereof together with one or more pharmaceutically acceptable diluents or carriers therefor.
A pharmaceutical combination comprising a) a first agent which is a S1P receptor agonist or a pharmaceutically acceptable salt thereof and b) a co-agent useful in the alleviation or treatment of brain degenerative diseases or progressive dementia.
A method for treating progressive dementia or brain degeneration or β-amyloid-related inflammatory diseases or disorders or for reducing or inhibiting loss of cognitive abilities in a subject in need thereof, comprising administering to said subject a therapeutically effective amount of a sphingosine-1-phosphate (SIP) receptor agonist or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.