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US 2013/0280820 A1Published application
Biomarkers for psoriasis
AssigneeSchering Corporation
InventorMARIBEL BEAUMONT
Life of this patent
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Abstract
A group of polypeptides that are modulated in a psoriatic sample as compared to a normal sample is provided. These polypeptides can be used as biomarkers for diagnosis and monitoring treatment of psoriasis.
Claims5
1-7. (canceled)
A method of managing the treatment of psoriasis in a subject comprising:
- a) determining first levels of vitronectin and hemopexin in a first plasma sample from the subject;
- b) determining second levels of vitronectin and hemopexin in a second plasma sample from the subject,
- wherein said first plasma sample is obtained before the second plasma sample;
- and
- c) increasing dosing of a drug to treat the psoriasis if, and only if, an elevated level of vitronectin and a decreased level hemopexin in the second sample compared with the first sample are observed.
2 more elements
9-19. (canceled)
21-23. (canceled)
Dependencies are inferred from the claim text.