Rapid multiplex lateral flow assay device
AssigneeArizona Board of Regents acting for and on behalf of Northern Arizona University
InventorsCatherine R. Propper, John T. Tester, Timothy L. Vail, Niranjan Venkatraman
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Abstract
Disclosed herein are devices, systems and methods for simultaneously conducting multiple assays on a liquid sample for the presence of, and/or quantification of, analytes in the liquid sample. The device, which is referred to herein as a multi-assay cartridge or multi-strip assay cartridge (MSC), may be used in a system comprised of the cartridge and a reading device or reader for reading the assays in the cartridge.
Claims23
A device, for simultaneously conducting multiple assays on a liquid sample, comprising the following:
- (a) a housing;
- (b) an inlet in the housing for introducing the liquid sample into the housing;
- (c) a diversion dam within the housing and in communication with the inlet;
- (d) a diversion dam channel within the housing and in communication with the diversion dam;
- (e) a first assay chamber and a second assay chamber within the housing, wherein the first assay chamber comprises a first assay for detecting the presence of an analyte in the liquid sample, and the second assay chamber comprises a second assay for detecting the presence of an analyte in the liquid sample;
- and
- (f) a first flow channel and a second flow channel, wherein
- the first flow channel is in communication with the diversion dam channel and the first assay chamber, and
- the second flow channel is in communication with the diversion dam channel and the second assay chamber.
A device for conducting assays on a liquid sample, comprising:
- (a) a housing;
- (b) an inlet in the housing for introducing the liquid sample into the housing;
- (c) an assay chamber within the housing comprising an assay for detecting the presence of an analyte in the liquid sample;
- and
- (d) means to join the device to a second device.
A method for simultaneously conducting multiple assays on a liquid sample, comprising:
- (i) introducing a liquid sample into a device comprising
- (a) a housing;
- (b) an inlet in the housing for introducing the liquid sample into the housing;
- (c) a diversion dam within the housing and in communication with the inlet;
- (d) a diversion dam channel within the housing and in communication with the diversion dam;
- (e) a first assay chamber and a second assay chamber within the housing, wherein the first assay chamber comprises a first assay for detecting the presence of an analyte in the liquid sample, and the second assay chamber comprises a second assay for detecting the presence of an analyte in the liquid sample;
- and
- (f) a first flow channel and a second flow channel, wherein
- the first flow channel is in communication with the diversion dam channel and the first assay chamber, and
- the second flow channel is in communication with the diversion dam channel and the second assay chamber;
- and
- (ii) reading results of each assay.
Dependencies are inferred from the claim text.