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AssigneesMassachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.
InventorsJeffrey M. Karp, Praveen Kumar Vemula, Nathaniel R. Campbell, Abdullah M. Syed, Sufeng Zhang, Omid C. Farokhzad, Robert S. Langer
Estimating the term…
Self-assembled gel compositions including a gelator, e.g., an enzyme-cleavable gelator, e.g., having a molecular weight of 2500 or less, are described. The self-assembled gel compositions can encapsulate one or more agents. Methods of making the self-assembled gel compositions, and methods of drug delivery using the self-assembled gel compositions are also described.
A self-assembled gel composition comprising an enzyme-cleavable, generally recognized as safe (GRAS) first gelator having a molecular weight of 2500 or less, wherein the GRAS first gelator is selected from the group consisting of ascorbyl alkanoate, sorbitan alkanoate, triglycerol monoalkanoate, sucrose alkanoate, glycocholic acid, and any combination thereof, and wherein the GRAS first gelator self-assembles into a gel comprising nano structures.
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A self-assembled gel composition comprising an enzyme-cleavable, generally recognized as safe (GRAS) first gelator having a molecular weight of 2500 or less and a non-independent second gelator.
Dependencies are inferred from the claim text.