Treatment of inflammatory bowel disease with 6-mercaptopurine
OwnerVered Rosenberger, Brenda Kolatch +2inventors
InventorsVered Rosenberger, Brenda Kolatch, Linda Susan Marshall, Anna Hotovely-Salomon
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Abstract
Methods of administering a delayed release 6-mercaptopurine pharmaceutical composition to patients suffering from inflammatory bowel disease which provide for release of the 6-mercaptopurine after passage of the pharmaceutical composition through the stomach are disclosed. The methods result in significant clinical improvement despite leading to very little systemic absorption of 6-mercaptopurine and also result in very few undesirable side effects.
Claims21
1-50. (canceled)
A method of treating inflammatory bowel disease (IBD) in a patient comprising administering a delayed release pharmaceutical composition comprising 6-mercaptopurine (6-MP) once per day for less than 12 weeks wherein the dose of 6-MP administered is not adjusted based on the patient's weight.
Dependencies are inferred from the claim text.