Back to results
US 2013/0280327 A1Published application
Zolpidem-based orodispersible pharmaceutical tablet
AssigneeSanofi
InventorsAnnick MARTINEZ, Olivier ROUGEOT, Yoshikatsu YAGUCHI
Life of this patent
Estimating the term…
Abstract
The present invention is directed to oral pharmaceutical forms for rapid disintegration which make it possible to prevent possible misuse of the zolpidem present therein. The present invention thus relates to a zolpidem-based orodispersible tablet formulation intended to prevent abuse of use of the tablet at the expense of a third party.
Claims31
An orodispersible pharmaceutical tablet, comprising zolpidem or one of its pharmaceutically acceptable salts;
- at least one disintegrating agent;
- at least one soluble agent of polyol type;
- and components which, if the tablet is introduced into an aqueous drink, which optionally comprises alcohol, generate visual means corresponding to an opacification of the drink and to at least one other visual means chosen from effervescence, the formation of insoluble particles, the flotation of the tablet, and combinations of these visual means, wherein the components generating the opacification of the drink comprise titanium dioxide particles.
Dependencies are inferred from the claim text.