Combination heptavalent vaccine
AssigneeBharat Biotech International Limited
InventorsGopinathan Kuppuswamy, Vijayanand Thiagarajan
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Abstract
The invention provides a stable immunogenic composition for prevention and prophylaxis of infections caused by rota virus, poliomyelitis virus, Haemophilius influenza, Hepatitis B, Corynebacterium diphtheriae, Clostridium tetani, Bordatella pertusis (acellular) in a single combined vaccine. The invention also provides for a bivalent immunogenic composition against rota virus and polio virus. The process of making such compositions of the multivalent antigens are also disclosed. The present invention also relates to the production and use of such vaccines for prophylaxis against the infections mentioned above.
Claims17
A stable immunogenic combination vaccine for prophylaxis and treatment against any genotypes or antigenic variants of rotavirus, poliomyelitis, pertussis, Hepatitis B, Haemophilus influenzae, diphtheria and tetanus infections, wherein any of the each component individual antigens is not impaired by the presence of other component antigens, thereby conferring an antibody titer equivalent or superior to the criterion for the seroprotection for each antigenic component.
A method of administering to a human individual an immunologically effective amount of IRV, IPV, aP (PT, FHA, p69 or PRN), HBS Ag, Hib-PRP-tt conjugate, DT and TT antigens for prophylaxis against disease caused by Rotavirus, poliomyelitis virus, acellullar Bordetella pertussis, Clostridium tetani, Corynebacterium diphtheriae, Hepatitis B virus, Haemophilus influenzae in one combined vaccine composition.
A method of administering to a human individual an immunologically effective amount of IRV and IPV antigens for prophylaxis and treatment against disease caused by Rotavirus and poliomyelitis virus in one combined vaccine composition.
Dependencies are inferred from the claim text.