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AssigneeCambridge Enterprise Limited
InventorsJohn Trowsdale, Alexander Barrow, Richard Farndale
Estimating the term…
This invention relates to the finding that collagen peptides bind to the osteoclast-associated receptor (OSCAR) and stimulate the activation and/or differentiation of OSCAR expressing cells, such as osteoclasts and osteoclast precursor cells. Collagen peptides are described which may be useful in the modulation of the differentiation and/or activation of OSCAR expressing cells, for example in the treatment of bone defects and disorders characterized by altered differentiation and/or activation of OSCAR expressing cells.
A method of treating a disorder characterized by altered osteoclast differentiation and/or activation comprising administering an antibody that binds to an osteoclast-associated receptor (OSCAR) to an individual in need thereof.
A method of treating rheumatoid arthritis comprising administering an antibody that binds to a human osteoclast-associated receptor (OSCAR) to an individual in need thereof.
A method for reducing a binding of an osteoclast-associated receptor (OSCAR) to a collagen comprising:
Dependencies are inferred from the claim text.