Osteoclastogenesis inhibitor containing anti-vdac antibody
AssigneeTokyo Women's Medical University
InventorsShigeru Kotaka, Yuki Nanke, Toru Yago, Manabu Kawamoto, Hisashi Yamanaka
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Abstract
The present invention provides a therapeutic agent or a preventative agent containing anti-VDAC antibody for diseases in which there is increased activation of osteoclasts, such as rheumatoid arthritis, and an inhibitor of human osteoclast formation containing anti-VDAC antibody.
Claims16
1-15. (canceled)
An osteoclastogenesis inhibitor comprising an anti-VDAC antibody, or a Fab fragment or a F(ab′)2 fragment thereof.
A method for inhibiting osteoclastogenesis, comprising an administrating an anti-VDAC antibody to a patient in need thereof.
A pharmaceutical composition for treating or preventing a disease having an increased activation of osteoclasts, comprising an anti-VDAC antibody, or a Fab fragment or a F(ab′)2 fragment thereof.
A method for treating or preventing a disease having an increased activation of osteoclasts, comprising an administrating an anti-VDAC antibody to a patient in need thereof.
Dependencies are inferred from the claim text.