Method for selecting patient to be given drug for treating septicemia

A method for selecting a patient to be administered a therapeutic agent for sepsis having an action mechanism that inhibits occurrence of Toll-like receptor 4-derived intracellular signaling, the method comprising the steps of:

• measuring sCD14-ST in a blood specimen derived from the subject,
• comparing the measured value with a cut-off value, and
• selecting the patient to be administered the therapeutic agent for sepsis when the measured value of the specimen is equal to or higher than the cut-off value and thus tests positive in comparison with the cut-off value.

A method for determining a timing for administering a therapeutic agent for sepsis having an action mechanism that inhibits occurrence of Toll-like receptor 4-derived intracellular signaling, the method comprising the steps of:

• measuring sCD14-ST in a blood specimen derived from a subject,
• comparing the measured value with a cut-off value, and
• selecting the subject as a patient being in a timing to be administered the therapeutic agent for sepsis when the measured value of the specimen tests positive in comparison with the cut-off value.

A method for setting a dosage of a therapeutic agent for sepsis having an action mechanism that inhibits occurrence of Toll-like receptor 4-derived intracellular signaling, the method comprising the steps of:

• measuring sCD14-ST in a blood specimen derived from a subject,
• comparing the measured value with a cut-off value, a step of selecting the subject as a patient to be administered the therapeutic agent for sepsis when the measured value of the specimen tests positive in comparison with the cut-off value, and
• setting a dosage of the therapeutic agent for sepsis based on the sCD14-ST concentration in the specimen.

A therapeutic agent for sepsis having an action mechanism that inhibits occurrence of Toll-like receptor 4-derived intracellular signaling, the therapeutic agent being administered to a subject suspected to have sepsis when a measured value obtained by measuring sCD14-ST in a blood specimen derived from the subject and compared with a cut-off value tests positive in comparison with the cut-off value.

A therapeutic agent for sepsis having an action mechanism that inhibits occurrence of Toll-like receptor 4-derived intracellular signaling, a dosage being set according to a concentration of sCD14-ST in a blood specimen derived from a subject suspected to have sepsis when a measured value of the specimen obtained by measuring sCD14-ST in the blood specimen and compared with a cut-off value tests positive in comparison with the cut-off value.