Methods of diagnosis and treatment for metabolic disorders
AssigneeDiaMedica Inc.
InventorMark S. Williams
Life of this patent
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Abstract
The invention relates to pharmaceutical compositions comprising tissue kallikrem (TK), and optionally a diabetes drug, a method of screening for a metabolic disorder by determining the concentration of TK and insulin in a biological sample from a test subject, a method of screening for a therapeutic agent for the treatment or prevention of a metabolic disorder, and a method for treating or preventing a metabolic disorder using a pharmaceutical composition comprising TK.
Claims9
1-34. (canceled)
A method for the treatment of insulin resistance in a subject with diabetes, comprising administering to the subject (a) a tissue kallikrein (KLK1) polypeptide and (b) an incretin or incretin mimetic.
Dependencies are inferred from the claim text.