Materials and methods relating to cell based therapies
AssigneeThe University Court of the University of Glasgow
InventorPaul Shiels
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Abstract
The invention relates to the provision of a novel cell population that can be used for tissue regeneration and the treatment of disease states associated with cell degeneration for age related tissue changes. The cell population are derived from adult stem/progenitor cells which are characterised by being positive or negative to the Thy1.1 cell marker.
Claims25
An isolated cell population originating from adult tissue, wherein said cells are capable of growth in a matrigel free culture system in the presence of serum;
- characterised in that the cells are Pdx-1 positive.
6-7. (canceled)
A method of isolating a bipotent stem cell population from adult mammalian tissue, said method comprising:
- culturing said adult mammalian tissue;
- isolating emergent cell population monolayer;
- and further isolating those cells which are positive for the cell surface marker Thy 1.1 thereby providing a bipotent stem cell population.
13-17. (canceled)
A method of isolating a bipotent stem cell population, said method comprising obtaining a population of cells as deposited under accession number Q6203 at ECACC on 12 May 2005;
- and isolating a sub-population of cells which are positive for the cell surface marker Thy 1.1.
(canceled)
25-26. (canceled)
29-36. (canceled)
Dependencies are inferred from the claim text.