Low-field nuclear magnetic resonance device and low-field nuclear magnetic resonance method

A low-field nuclear magnetic resonance device comprising:

• a dynamic nuclear polarization (DNP) amplification unit to amplify the nuclear polarization of hydrogen atoms of water using a DNP-possible substance (DNP substance) to provide the amplified nuclear polarization to a measurement target;
• a sensor unit to measure a magnetic resonance signal of the measurement target using a SQUID sensor or an optically-pumped atomic magnetometer;
• and
• a measurement magnetic field coil to apply a measurement magnetic field to the measurement target,
• wherein the DNP amplification unit comprises:
• a bias magnetic field coil to apply a bias magnetic field to a DNP substance in an aqueous solution state;
• and
• an RF resonance circuit part including an RF resonance coil disposed around the bias magnetic field coil, and
• wherein the measurement target includes the DNP substance in the aqueous solution state.

A low-field nuclear magnetic resonance device comprising:

• a dynamic nuclear polarization (DNP) amplification unit to amplify the nuclear polarization of hydrogen atoms of water using a DNP-possible substance (DNP substance) to provide the amplified nuclear polarization to a measurement target;
• a sensor unit to measure a magnetic resonance signal of the measurement target using a SQUID sensor or an optically-pumped atomic magnetometer;
• and
• a measurement magnetic field coil to apply a measurement magnetic field to the measurement target,
• wherein the DNP amplification unit comprises:
• a bias magnetic field coil to apply a bias magnetic field to the DNP substance and the water;
• a filter unit disposed inside the bias magnetic field coil and including a gel-filtration matrix to provide the amplified nuclear polarization of the water to the measurement target;
• and
• an RF resonance circuit part including an RF resonance coil disposed around the gel-filtration matrix, and
• wherein the DNP amplification unit, the measurement target, the sensor unit, and the measurement magnetic field coil are disposed spatially adjacent to each other to reduce a signal decay caused by a relaxation of the amplified nuclear polarization of the water while providing the amplified nuclear polarization of the water.

A low-field nuclear magnetic resonance method comprising:

• amplifying the nuclear polarization of hydrogen atoms of water by applying a bias magnetic field and an RF magnetic field to the DNP substance and the water;
• providing the amplified nuclear polarization of the water to a measurement target;
• applying a measurement magnetic field to the measurement target;
• and
• measuring a nuclear magnetic resonance signal of the measurement target using a SQUID or an optically-pumped atomic magnetometer.