Systems And Methods For Measuring Mitochondrial Capacity
AssigneeUniversity of Georgia Research Foundation, Inc.
InventorsKevin K. McCully, Terence E. Ryan
Life of this patent
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Abstract
In one embodiment, measuring mitochondrial capacity includes performing arterial occlusions on a patient, measuring oxygenated hemoglobin/myoglobin and deoxygenated hemoglobin/myoglobin within the patient's body during the occlusions, calculating a blood volume correction factor that accounts for a change in blood volume that occurs during the arterial occlusions, and applying the correction factor to the measured oxygenated hemoglobin/myoglobin and deoxygenated hemoglobin/myoglobin measurements to obtain correct oxygenated hemoglobin/myoglobin and deoxygenated hemoglobin/myoglobin measurements.
Claims20
A method for measuring mitochondrial capacity, the method comprising:
- performing arterial occlusions on a patient;
- measuring oxygenated hemoglobin/myoglobin and deoxygenated hemoglobin/myoglobin within the patient's body during the occlusions;
- calculating a blood volume correction factor that accounts for a change in blood volume that occurs during the arterial occlusions;
- and
- applying the correction factor to the measured oxygenated hemoglobin/myoglobin and deoxygenated hemoglobin/myoglobin measurements to obtain corrected oxygenated hemoglobin/myoglobin and deoxygenated hemoglobin/myoglobin measurements.
A system for measuring mitochondrial capacity, the system comprising:
- a processor;
- and
- memory that stores a mitochondrial capacity measurement system having logic configured to:
- receive oxygenated hemoglobin/myoglobin and deoxygenated hemoglobin/myoglobin measurements obtained from a patient,
- calculate a blood volume correction factor that accounts for a change in blood volume that occurs during the arterial occlusions, and
- apply the correction factor to the oxygenated hemoglobin/myoglobin and deoxygenated hemoglobin/myoglobin measurements.
Dependencies are inferred from the claim text.