Spray dried powder formulation for vaccines entrapping alum and the antigen in biodegradable polymer particles
AssigneeNational Institute of Immunology
InventorsAmulya Kumar Panda, Anish Chakkunkal, Dinesh Giri Goswami
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Abstract
The present invention relates to a novel effective dry powder vaccine formulation that increases the immune response in the host. The formulation comprises of an antigen entrapped into a polymer particle, coated with alum, finally spray dried into a dry powder. This formulation is used to elicit long lasting higher antibody titers than alum adsorbed antigen or admixture of polymer entrapped antigen and alum.
Claims16
A vaccine formulation for eliciting the long lasting higher antibody titre comprising an antigen entrapped into a biodegradable polymer co entrapped with alum.
Dependencies are inferred from the claim text.