Compositions and methods for diagnosing and treating an inflammation
AssigneeRappaport Family Institute for Research in the Medical Sciences
InventorsNathan KARIN, Gizi Wildbaum, Rachel Anunu, Yaniv Zohar, Nir Netzer
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Abstract
A method of reducing an inflammatory response in a subject is provided. The method comprising providing to a subject in need thereof a therapeutically effective amount of an agent capable of reducing activity and/or expression of a scavenger receptor or of an effector thereof, thereby reducing the inflammatory response in the subject.
Claims14
A method of treating an autoimmune inflammatory disease in a subject in need thereof, the method comprising administering to said subject a therapeutically effective amount of an anti-SR-B1 antibody, thereby treating the autoimmune inflammatory disease in the subject, wherein said autoimmune inflammatory disease is selected from the group consisting of Systemic Lupus Erythematosus (SLE), Amyotrophic Lateral Sclerosis (ALS) and Rheumatoid Arthritis (RA).
Dependencies are inferred from the claim text.