Ocular delivery systems and methods

A method for reducing intraocular pressure comprising:

• a) advancing a cannula at least partially through the anterior chamber of the eye;
• b) entering Schlemm's canal at a single access point using the cannula;
• and
• c) delivering a volume of a viscoelastic fluid through a conduit slidable within, and extendable from, the cannula, sufficient to disrupt the structure of Schlemm's canal and surrounding tissues to reduce intraocular pressure.

A method for treating conditions of the eye comprising:

• a) entering Schlemm's canal using a conduit extendable from a single-operator controlled handle, the handle comprising a fluid reservoir;
• and
• b) delivering a volume of a viscoelastic fluid from the fluid reservoir through the conduit by increasing pressure within the fluid reservoir,
• wherein the volume of delivered viscoelastic fluid is sufficient to disrupt the structure of Schlemm's canal and surrounding tissues to reduce intraocular pressure.

A device for delivering fluids comprising:

• a cannula;
• a conduit slidably disposed within, and advanceable distally from, the cannula;
• a handle coupled to the cannula, wherein a portion of the handle defines a fluid reservoir;
• and
• a linear gear moveable to advance a fluid from the fluid reservoir through the conduit.