Process for preparing prostaglandin derivatives
AssigneeYonsung Fine Chemical Co., Ltd.
InventorsChangyoung OH, Kee Young LEE, Yong Hyun KIM, Jae Eun JOO
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Abstract
The present invention relates to a process for preparing a prostaglandin derivative and an intermediate therefor. In accordance with the present invention, the prostaglandin F (PGF) derivative can be efficiently prepared with high purity by removing the protecting group of a protected prostaglandin E (PGE) derivative obtained from conjugate addition and then stereoselectively reducing the ketone group on the cyclopentanone ring of the PGE derivative.
Claims4
Travoprost having a purity of 99.5% or more.
Bimatoprost having a purity of 99.5% or more.
A compound of the following formula (8):
A compound of the following formula (9):
Dependencies are inferred from the claim text.