Hydrophobic intraocular lens

A composition comprising at least one copolymer comprising:

• (a) one or more first monomeric subunits comprising a polymerized acrylate or methacrylate group, at least one side group comprising (i) an aryloxy moiety, and (ii) an aliphatic carbon moiety linking the aryloxy moiety with the polymerized acrylate or methacrylate group, wherein the aliphatic carbon moiety comprises at least one hydroxyl substituent, and
• (b) one or more second monomeric subunits different from the first monomeric subunits comprising a polymerized acrylate or methacrylate group, and comprising at least one alkoxyalkyl side group,
• (c) one or more third monomeric subunits different from the first and second monomeric subunits, the third monomeric subunits comprising a polymerized acrylate or methacrylate group, and comprising at least one alkylene oxide side group,
• wherein the first monomeric subunit is present in a greater amount by weight than the second monomeric subunit, and the first and second monomeric subunits together comprise about 75 percent or more of the monomeric subunits composition by weight.

A method for making a composition comprising at least one copolymer comprising monomeric subunits comprising:

• preparing a co-monomer mixture comprising:
• (a) one or more first monomers comprising a polymerizable acrylate or methacrylate group, at least one side group comprising (i) an aryloxy moiety, and (ii) an aliphatic carbon moiety linking the aryloxy moiety with the polymerizable acrylate or methacrylate group, wherein the aliphatic carbon moiety comprises at least one hydroxyl substituent, and
• (b) one or more second monomers different from the first monomer(s) comprising a polymerizable acrylate or methacrylate group, and comprising at least one alkoxyalkyl side group,
• (c) one or more third monomers different from the first and second monomers, the third monomers comprising a polymerizable acrylate or methacrylate group, and comprising at least one alkylene oxide side group,
• wherein the first monomer(s) is present in a greater amount by weight than the second monomer(s), and the first and second monomers together comprise at least about 75 percent or more of the monomers by weight;
• polymerizing the co-monomer mixture.

An intraocular lens comprising at least one copolymer consisting essentially of:

• (a) one or more first monomeric subunits consisting essentially of a polymerized acrylate or methacrylate group, at least one side group comprising (i) an aryloxy moiety, and (ii) an aliphatic carbon moiety linking the aryloxy moiety with the polymerized acrylate or methacrylate group, wherein the aliphatic carbon moiety consists essentially of at least one hydroxyl substituent, and
• (b) one or more second monomeric subunits different from the first monomeric subunits consisting essentially of a polymerized acrylate or methacrylate group, and consisting essentially of at least one alkoxyalkyl side group,
• (c) one or more third monomeric subunits different from the first and second monomeric subunits, the third monomeric subunits consisting essentially of a polymerized acrylate and/or methacrylate group, and consisting essentially of at least one alkylene oxide side group,
• (d) one or more fourth monomeric subunits different from the first, second, and third monomeric subunits that are crosslinked subunits,
• wherein the first monomeric subunit is present in a greater amount by weight than the second monomeric subunit, and the first and second monomeric subunits together consist essentially of about 75 percent or more of the monomeric subunits composition by weight.

A composition comprising a co-monomer mixture comprising:

• (a) one or more first monomers comprising a polymerizable acrylate or methacrylate group, at least one side group comprising (i) an aryloxy moiety, and (ii) an aliphatic carbon moiety linking the aryloxy moiety with the polymerizable acrylate or methacrylate group, wherein the aliphatic carbon moiety comprises at least one hydroxyl substituent, and
• (b) one or more second monomers different from the first monomer(s) comprising a polymerizable acrylate or methacrylate group, and comprising at least one alkoxyalkyl side group,
• (c) one or more third monomers different from the first and second monomers, the third monomers comprising a polymerizable acrylate or methacrylate group, and comprising at least one alkylene oxide side group,
• wherein the first monomer(s) is present in a greater amount by weight than the second monomer(s), and the first and second monomers together comprise about 75 percent or more of the monomers by weight.