Injectable Cross-Linked Polymeric Preparations and Uses Thereof

A method of treating damaged cardiac tissue in a subject in need thereof, comprising administering a pharmaceutical preparation containing a cross-linked alginate polymer by injection into damaged cardiac tissue of the subject, thereby treating the damaged cardiac tissue, wherein the pharmaceutical preparation is cross-linked by multivalent cations and has an elastic response equal to or greater than a viscous response, the alginate is present in an amount ranging from 0.1 to 4% (w/v) with a molecular weight ranging from 1 to 300 kDa, and a multivalent cation salt to polymer salt ratio ranges between 2:1 and 1:10.