Inhibitors of Human Immunodeficiency Virus Replication

A compound of Formula I

• where:
• X is C or N;
• R1 is hydrogen or Ar1;
• R2 is hydrogen or Ar1;
• provided that when X is C either R1 is Ar1 and R2 is hydrogen or R2 is Ar1 and R1 is hydrogen, and when X is NR1 is Ar1 and R2 is hydrogen;
• R3 is N(R6)(R7);
• R4 is alkyl or haloalkyl;
• R5 is alkyl;
• R6 is hydrogen or alkyl;
• R7 is hydrogen or alkyl;
• or N(R6)(R7) taken together is azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, homopiperidinyl, homopiperazinyl, or homomorpholinyl, and is substituted with 0-3 substituents selected from halo, alkyl, haloalkyl, hydroxy, alkoxy, haloalkoxy, carboxy, or carboxamido;
• or N(R6)(R7) taken together is indolinyl, isoindolinyl, tetrahydroisoquinolinyl, or decahydroisoquinolinyl, and is substituted with 0-3 substituents selected from halo, alkyl, haloalkyl, hydroxy, alkoxy, haloalkoxy, carboxy, or carboxamido;
• or N(R6)(R7) taken together is a [4.2.0,], [4.3.0,], [4.4.0,], [4.5.0,], [4.6.0,], [5.2.0,], [5.3.0,], [5.4.0,], [5.5.0,], [5.6.0,], [6.2.0,], [6.3.0,], [6.4.0,], [6.5.0,], [6.6.0,] spirocyclic amine;
• or N(R6)(R7) taken together is
• and
• Ar1 is phenyl, pyridinyl, or biphenyl and is substituted with 0-3 substituents selected from halo, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkoxy, haloalkoxy, phenyl, benzyl, phenoxy, and benzyloxy wherein said phenyl, benzyl, phenoxy, and benzyloxy is substituted with 0-3 halo, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkoxy, and haloalkoxy substituents;
• or Ar1 is tetralinyl, ((methyl)indazolyl)phenyl, or (benzyloxy)phenyl;
• or a pharmaceutically acceptable salt thereof.