Devices, systems and methods for loading samples
AssigneePerkinElmer Health Sciences, Inc.
InventorsNigel Thornton Hopley White, Steven Edward Liebold, Gary Vincent Millard
Life of this patent
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Abstract
Certain embodiments described herein are directed to devices and system that can be used to fill a sample cell. In some examples, the system can be configured with a pressure device configured to provide a negative pressure to accelerate filling of the cell with the sample. In some embodiments, the negative pressure can be used to fill a flow cell at a selected fill rate.
Claims21
A system comprising:
- a sample introduction device;
- a flow cell fluidically coupled to the sample introduction device and configured to receive sample from the sample introduction device through a fluid inlet of the flow cell;
- a sensor coupled to the fluid inlet of the flow cell and configured to determine the time of arrival of sample at the fluid inlet of the flow cell;
- a valve fluidically coupled to the flow cell;
- and
- a pressure device fluidically coupled to the flow cell when the valve is in a second state and fluidically decoupled from the flow cell when the valve is in a first state.
A system comprising a flow cell fluidically coupled to a valve and a pressure device when the valve is in a second state, in which the flow cell is fluidically decoupled from the pressure device when the valve is in a first state, the pressure device configured to provide a negative pressure when the valve is in the second state to accelerate flow of sample into the flow cell.
21-89. (canceled)
Dependencies are inferred from the claim text.