Distribution Wide Estimated Risk Scoring to Decrease the Probability of Covariate Imbalances Adversely Affecting Randomized Trial Outcomes
OwnerWilliam J. DWYERinventor
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OwnerWilliam J. DWYERinventor
Estimating the term…
In certain situations, such as clinical trials, random or semi-random trials may be used to evaluate an outcome of interest. The outcome of such randomized trials may be affected by variables known as “covariates” which, individually or in combination, interact with the underlying subject matter under study. When designing such a trial, it may be important to select an appropriate randomization scheme so that covariates of interest are evenly distributed among test groups. The present application provides a scoring system to compare the effectiveness of randomization schemes in decreasing the probability that covariates of interest will be imbalanced. Furthermore, methods, mediums, and systems are described herein for choosing a randomization scheme in order to improve the quality and predictive value of a randomized study.
An electronic-device implemented method comprising:
A non-transitory electronic-device readable medium storing instructions that, when executed by one or more processors, cause the one or more processors to:
A system comprising:
A system comprising:
Dependencies are inferred from the claim text.