Method of Establishing Mouse Strain
AssigneeNational University Corporation Kumamoto University
InventorsMasatake Araki, Kimi Araki
Life of this patent
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Abstract
A method of producing a chimera animal, characterized by transplanting, into a host animal, an aggregate of a first pluripotent stem cell that is of interest to strain establishment, a second pluripotent stem cell in which the ability to form germ cells is absent or decreased, and embryo.
Claims7
A method for producing a chimeric animal, comprising the step of transferring an aggregate of a first pluripotent stem cell that is of interest to strain establishment, a second pluripotent stem cell associated with lack or low ability to form germ cells and an embryo into a host animal.
A helper cell for enhancing strain establishment efficiency of a pluripotent stem cell that is of interest to the strain establishment, wherein the helper cell is made of a pluripotent stem cell associated with lack or low ability to form germ cells.
A helper cell for enhancing strain establishment efficiency of a pluripotent stem cell that is of interest to the strain establishment, wherein the helper cell is made of a cell identified by accession number NITE BP-973, receipt number NITE ABP-1135 or receipt number NITE ABP-1136.
Dependencies are inferred from the claim text.