Moesin fragments and uses thereof
AssigneeShanghai Kexin Biotech Co., Ltd.
InventorsXiaofeng Zeng, Yue Zhang, Zhinan Shou, Hua Mao, Hongbin Sun, Jie Qian, Yongjun Han, Weina Situ
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Abstract
The present invention provides compositions and methods useful for detecting and monitoring autoimmune diseases.
Claims23
A composition comprising a moesin fragment capable of binding to an anti-moesin autoantibody, wherein the moesin fragment comprises at least ten consecutive amino acid residues from a human moesin protein domain, wherein the human moesin protein domain is selected from the group consisting of the N-terminal FERM domain (SEQ ID NO:2), the helical domain (SEQ ID NO:4) and the C-terminal tail domain (SEQ ID NO:5), and wherein the moesin fragment is not a full length human moesin protein.
10-20. (canceled)
(canceled)
28-32. (canceled)
Dependencies are inferred from the claim text.