Endoscopic systems and methods for resection of tissue

A method for facilitating resection of tissue, the method comprising:

• providing apparatus comprising a first tube having proximal and distal regions, a second tube disposed circumferentially around at least a portion of the distal region of the first tube, and a wire having a distal end securely attached to a distal region of the second tube;
• positioning at least a segment of tissue within a working lumen of the first tube;
• and
• circumferentially rotating the second tube relative to the distal region of the first tube to pass the wire circumferentially over a distal face of the first tube to incise the segment of tissue disposed within the working lumen of the first tube.

Apparatus for facilitating resection of tissue, the apparatus comprising:

• a first tube having a working lumen;
• a second tube disposed circumferentially around at least a portion of the first tube;
• and
• a wire having a distal end securely attached to a distal region of the second tube,
• wherein at least one of the first and second tubes comprises a sharpened distal face configured to puncture tissue such that a segment of tissue is subsequently disposed within the working lumen of the first tube, and
• wherein rotation of the second tube relative to the first tube causes the wire to pass circumferentially over a distal face of the first tube to incise the segment of tissue disposed within the working lumen of the first tube.