System and apparatus for cell treatment
AssigneeThe General Hospital Corporation D/B/A
InventorWilliam G. Austen, JR.
Life of this patent
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Abstract
The present invention relates to systems and apparatuses for improving quality and viability of biological material, such as harvested adipose cells, stem cells, or other cells or biological components, by treatment of the biological material with membrane-repairing/stabilizing agents or the like and/or mechanical removal of components, such as impurities and/or excess treatment agents. The present invention further relates to systems and apparatuses for transplanting tissue, such as adipose tissue.
Claims28
An apparatus comprising
- a chamber having at least one outlet;
- and
- a pressure generating device configured and arranged for generating a positive pressure within the chamber that is at or below a predetermined threshold, the positive pressure being sufficient to cause a biological material, if present in the chamber, to discharge through the outlet, wherein the predetermined threshold is a pressure above which the biological material has relatively low viability as a tissue graft following discharge from the outlet into a graft site in a subject.
(canceled)
(canceled)
A apparatus comprising,
- a chamber having at least one inlet and at least one outlet;
- a pressure generating device configured and arranged for transferring a biological material into the chamber through the at least one inlet and discharging a processed biological material out from the chamber through the at least one outlet;
- and
- at least one retention matrix within the chamber configured and arranged for contacting the biological material, when present in the chamber, such that a fraction of the biological material is retained in the retention matrix.
23-52. (canceled)
55-57. (canceled)
An apparatus for treating a biological material for transplantation, comprising:
- a chamber having at least one open end;
- and
- a plurality of end-pieces, wherein at least one end-piece is configured to be removably affixed to the at least one open end;
- and
- wherein the chamber is configured to hold the biological material;
- and
- wherein the plurality of end-pieces comprises a filter, an arrangement configured to introduce the biological material into the chamber, a plunger arrangement, a needle arrangement, or an absorbent material or adsorbent material.
59-70. (canceled)
Dependencies are inferred from the claim text.