Devices for Delivering a Medicament and Connector for Same

A connector interface configured for substantially permanent use or single use, the interface comprising:

• an inner connection configured as a two-element luer-lock including a tabbed hub of a female fitting element that rotatingly engages into threads within a sleeve of a male fitting element;
• where the sleeve includes a notched cylinder end, including at least two notches;
• where a base portion of the female fitting element includes at least two teeth that rotate engage lockingly into the at least two notches when the tabbed hub is fully engaged with the threads;
• where the notches include a first face at an acute angle relative to a plane defined by the cylinder end and a second face at substantially a perpendicular angle relative to said plane;
• and
• where counter-rotation brings the teeth into locking contact with the second face of the notches that effectively stops counter-rotation.

A connector interface comprising:

• a first connector element and a second connector element;
• wherein the first connector element includes
• a first cylindrical female portion disposed coaxially around
• a first cylindrical male engaging portion, and
• a first engaging end defined by corresponding termini of the first cylindrical male portion and the first cylindrical female portion;
• wherein the second connector element includes
• a second cylindrical female portion that engagingly receives therein the first male portion,
• the second cylindrical female portion circumferentially defined by a second cylindrical male portion that engages into the first female portion, and
• a second engaging end defined by a co-terminus of the second cylindrical male portion and the second cylindrical female portion;
• wherein the first male portion is circumferentially coaxially encompassed by the first female portion;
• wherein the first female portion includes at least one inward-facing helically threaded surface that is complementary to and that engagingly receives at least one tab radially protruding externally from the second male portion;
• and
• wherein an external surface of the second male portion includes a first plurality of generally longitudinal teeth opposite the second engaging end, and the first engaging end includes a second plurality of notches complementary to and that lockingly receive an end portion of the first plurality of longitudinal teeth when the at least one tab is fully engaged with the at least one inward-facing helically threaded surface;
• wherein the at least one tab, the at least one inward-facing helically threaded surface, the first engaging end, the second engaging end, and the longitudinal teeth are dimensioned and longitudinally spaced relative to each other such that substantially complete engagement between the first connector element and second connector element forms an effective fluid-patent seal and forms a locked relationship between the at least one plurality of notches and the notches.

A device configured for fluid delivery via a patient nostril, the device comprising:

• an introducer and an injector;
• the injector including:
• an elongate injector tube defining a central longitudinal axis and including a channel-engaging lateral projection near a first injector end, and
• at least one injector tube aperture near a second injector end, the second injector end disposed longitudinally opposite the first injector end;
• the introducer including:
• a first introducer end;
• a second introducer end longitudinally opposite the first introducer end;
• a generally cylindrical elongate body wall defining a longitudinal, generally cylindrical, lumen that extends between the first introducer end and the second introducer end;
• wherein the lumen includes at least two longitudinal channels parallel to each other, the channels forming a depressed track along a lumen-facing body wall surface;
• where the longitudinal channels merge to form a single channel near the first end such that the complete channel forms a generally goalpost-shaped, U-shaped or Y-shaped configuration;
• and
• where the injector tube aperture is disposed at a first radial angle relative to the longitudinal axis when the channel-engaging projection is in one of the at least two longitudinal channels, and is disposed at a second radial angle relative to the longitudinal axis when the channel-engaging projection is in another of the at least two longitudinal channels, where the first and second radial angles correspond the angle required for a spray path access to a patient's sphenopalatine ganglion region from, respectively, that patient's right and left nostrils, and where the injector tube, projection, and channels are longitudinally dimensioned to extend and orient the aperture toward that region.

A device for delivering a medicament to a patient in need thereof, the device having:

• an injector comprising a first end configured to remain outside a patient's nasal passage and a second end configured for entry into the patient's nasal passage;
• and an introducer configured for engagement into a nostril of the patient and comprising a passageway configured for receiving the injector;
• wherein the injector is moveable—relative to the introducer—between a storage position preceding the engagement and an engaging position pursuant to the engagement, where said engagement position is different from the storage position as the injector is extended outward from the introducer;
• and
• wherein the engaging position is configured such that the second end of the injector is situated medial and/or posterior and/or inferior to a sphenopalatine ganglion of a patient;
• wherein the second end of the injector comprises one or a plurality of apertures configured for dispersing a medicament superiorly and/or laterally and/or anteriorly towards the sphenopalatine ganglion;
• and
• wherein the injector comprises a channel that extends from the first end to the one or a plurality of apertures at the second end and that is configured to receive a medicament and to communicate the medicament to the one or a plurality of apertures;
• and
• wherein the improvement comprises:
• the introducer passageway further including at least two longitudinal channels that are generally parallel to each other, the channels forming a depressed track along a passageway-facing body wall surface, where the longitudinal channels merge to form a single channel near the first end such that the complete channel forms a generally goalpost-shaped, U-shaped or Y-shaped configuration;
• the injector further comprising a channel-engaging lateral projection near a first injector end, said projection engaged selectably into the channels such that orientation of the projection into a second end of either of the longitudinal channels, opposite the first end, corresponds to the engaging position.