Fluid Exchange Catheter System

A method of infusing and aspirating fluid from the body, comprising:

• a) providing a catheter system, comprising:
• i) an inner lumen having a proximal end and a distal end, wherein the proximal end of the inner lumen is connected to an infusion fluid source;
• ii) an infusion mechanism operably connected with the inner lumen;
• iii) an outer lumen having a proximal end, a distal end and a lumen wall extending between the proximal end and the distal end forming an interior lumen space, wherein the distal end of the inner lumen is disposed within the interior lumen space;
• and
• iv) an aspiration mechanism operably connected with the outer lumen;
• b) activating the infusion mechanism to infuse fluid from the infusion fluid source through the inner lumen and into the body for an infusion time period and at an infusion pressure and infusion flow rate while the aspiration mechanism is disabled;
• c) disabling the infusion mechanism to stop infusion;
• d) activating the aspiration mechanism to aspirate fluid from the body through the aspiration lumen for an aspiration time period and at an aspiration pressure and aspiration flow rate while the infusion mechanism is disabled;
• e) disabling the aspiration mechanism to stop aspiration;
• f) repeating steps b) through e);
• and
• g) periodically dispersing a fluid jet from the inner lumen against an exchange surface disposed at the distal end of the outer lumen.

A method of infusing and aspirating fluid from the body, comprising:

• a) providing a catheter system, comprising:
• i) an inner lumen having a proximal end and a distal end, wherein the proximal end of the inner lumen is connected to an infusion fluid source;
• ii) an infusion mechanism operably connected with the inner lumen;
• iii) an outer lumen having a proximal end, a distal end and a lumen wall extending between the proximal end and the distal end forming an interior lumen space, wherein the distal end of the inner lumen is disposed within the interior lumen space;
• and
• iv) an aspiration mechanism operably connected with the outer lumen;
• b) activating the infusion mechanism to infuse fluid from the infusion fluid source through the inner lumen and into the body for an infusion time period and at an infusion pressure and infusion flow rate while the aspiration mechanism is disabled;
• c) disabling the infusion mechanism to stop infusion;
• d) activating the aspiration mechanism to aspirate fluid from the body through the aspiration lumen for an aspiration time period and at an aspiration pressure and aspiration flow rate while the infusion mechanism is disabled;
• e) disabling the aspiration mechanism to stop aspiration;
• f) repeating steps b) through e);
• g) periodically dispersing a fluid jet from the inner lumen against an exchange surface disposed at the distal end of the outer lumen;
• h) monitoring at least one of the infusion pressure, the infusion flow rate, the aspiration pressure, and the aspiration flow rate;
• and
• i) disabling at least one of the infusion mechanism and the aspiration mechanism if the infusion pressure, infusion flow rate, aspiration pressure, or aspiration flow rate is outside of a predetermined range.

A method of treating an extra-cellular fluid or pathological liquid accumulation in a portion of body tissue using a catheter system, comprising:

• a) providing the catheter system, the catheter system comprising:
• i) an inner lumen having a proximal end and a distal end;
• ii) an infusion mechanism operably connected with the inner lumen;
• iii) an outer lumen having a proximal end, a distal end and a lumen wall extending between the proximal end and the distal end forming an interior lumen space, wherein the distal end of the inner lumen is disposed within the interior lumen space;
• and
• iv) an aspiration mechanism operably connected with the outer lumen;
• b) positioning the distal end of the inner lumen and the distal end of the outer lumen in fluid communication with the extra-cellular fluid or pathological liquid accumulation;
• c) activating the infusion mechanism to infuse an infusion fluid through the inner lumen and into contact with the extra-cellular fluid or pathological liquid accumulation;
• d) disabling the infusion mechanism to stop infusion;
• and
• e) activating the aspiration mechanism to aspirate at least a portion of the extra-cellular fluid or pathological liquid accumulation,
• wherein the aspiration mechanism is disabled at least during step c) and the infusion mechanism is disabled at least during step e).