Optimized promoter sequence
AssigneeHer Majesty the Queen in right of Canada, as represented by the Minister of Health
InventorsGary Kobinger, Heinz Feldmann, Kaylie Tran
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Abstract
A modified CAG promoter which is capable of driving high levels of expression of sequences of interest inserted downstream therefrom is herein described.
Claims8
A purified or isolated functional promoter element having at least 70% identity with the nucleotide sequence as set forth in SEQ ID No. 1.
A nucleotide sequence encoding a CAG promoter sequence as set forth in SEQ ID No. 1.
A nucleotide sequence comprising the CAG promoter sequence as set forth in SEQ ID No. 1 operably linked to a nucleic acid sequence comprising a Kozak sequence and a nucleic acid sequence encoding a codon-optimized Ebola virus glycoprotein as set forth in SEQ ID No. 2.
Dependencies are inferred from the claim text.