Silk fibroin materials and use thereof
AssigneesMassachusetts Institute of Technology, Trustees of Tufts College
InventorsDavid L. Kaplan, Rina Nazarov, Gordana Vunjak-Novakovic, Lorenz Meinel
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Abstract
The present invention provides processes for producing porous silk fibroin scaffold material. The porous silk fibroin scaffold can be used for tissue engineering. The porosity of the silk fibroin scaffolds described herein can be adjusted as to mimic the gradient of densities found in natural tissue. Accordingly, methods for engineering of 3-dimensional tissue, e.g. bone and cartilage, using the silk fibroin scaffold material are also provided.
Claims5
A composition comprising a three-dimensional silk fibroin body, wherein the silk fibroin comprises a beta-sheet structure.
Dependencies are inferred from the claim text.