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US 2013/0158079 A1Published application
Clevidipine emulsion formulations containing antimicrobial agents
AssigneeThe Medicines Company
InventorsRajeshwar Motheram, Gregory Charles Williams
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Abstract
Pharmaceutical formulations comprising clevidipine in an oil-in-water formulation that is resistant to microbial growth and stable against the formation of impurities.
Claims13
A pharmaceutical formulation comprising,
- (a) an effective amount of clevidipine, or a pharmaceutically acceptable salt or ester,
- (b) an antimicrobial agent, present at about 0.001 to about 1.5% w/v,
- (c) a lipid,
- (d) an emulsifier,
- (e) a tonicity modifier, and
- (f) water
- wherein the formulation is resistant to microbial growth.
4 more elements
Dependencies are inferred from the claim text.