Hypercholesterolemia and tendinous injuries
AssigneeThe Trustees of the University of Pennsylvania
InventorsJoseph A. ABBOUD, Louis J. SOSLOWSKY
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Abstract
This invention provides compositions and methods of inhibiting, suppressing, or treating a tendinous or musculoskeletal soft tissue injury. The invention further provides a method of ameliorating symptoms associated with a tendinous or musculoskeletal soft tissue injury. Additionally, the invention provides methods for evaluating the risk of developing a tendinous or musculoskeletal soft tissue injury.
Claims26
A method of treating a tendinous or musculoskeletal soft tissue injury, in a subject with hypercholesterolemia, comprising systemically administering to said subject with hypercholesterolemia a therapeutically effective amount of a cholesterol lowering agent, wherein said soft tissue injury is a tendon injury.
A method of reducing the incidence of a tendinous or musculoskeletal soft tissue injury, in a subject with hypercholesterolemia and at risk of developing a tendon injury, comprising systemically administering to said subject with hypercholesterolemia a therapeutically effective amount of a cholesterol lowering agent, wherein said soft tissue injury is a tendon injury.
Dependencies are inferred from the claim text.