Prevention Of Pancreatic Beta Cell Degeneration
OwnerAndrew G. Reaume, Michael S. Saporito +1inventors
InventorsAndrew G. Reaume, Michael S. Saporito, Alexander R. Ochman
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Abstract
The present invention relates to compounds and pharmaceutically acceptable salts thereof and formulations comprising the compounds or a pharmaceutically acceptable salts thereof that are useful in methods of preventing pancreatic beta cell degeneration or methods of treating a disorder associated with pancreatic beta cell degeneration, such as type I diabetes.
Claims12
1-9. (canceled)
A method of preventing pancreatic beta cell degeneration, treating a disorder associated with pancreatic beta cell degeneration, or treating or preventing type I diabetes in a mammal comprising administering to the mammal in need thereof an effective amount of a composition comprising a compound of formula:
- wherein R1 is an alkyl group;
- X is a halogen;
- n is an integer from 0 to 5 and m is 0 or 1, wherein m+n is less than or equal to 5.
A method of preventing pancreatic beta cell degeneration, treating a disorder associated with pancreatic beta cell degeneration, or treating or preventing type I diabetes in a mammal comprising administering to the mammal in need thereof an effective amount of a composition comprising a compound of formula:
- wherein R1 is an alkyl group and n is an integer from 0 to 5.
20-91. (canceled)
Dependencies are inferred from the claim text.