Novel compounds
AssigneeBoehringer Ingelheim International GmbH
InventorsKlaus RUDOLF, Daniel BISCHOFF, Georg DAHMANN, Matthias GRAUERT, Raimund KUELZER, Bernd WELLENZOHN
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Abstract
This invention relates to compounds of formula I their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, X, R1, R2, R3 have meanings given in the description.
Claims4
A compound of formula I
- in which
- R1 represents phenyl or
- X represents
- the group
- or a physiologically acceptable salt thereof.
A compound selected from the group consisting of
- or a physiologically acceptable salt thereof.
Dependencies are inferred from the claim text.