Pharmaceutical compositions and methods for treating gastrointestinal infections and disorders
AssigneeGilead Sciences, Inc.
InventorsUri Aryeh Lopatin, Daniel B. Tumas
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Abstract
Methods of treating gastrointestinal disorders, in a patient in need thereof, including disorders of the liver and pancreas, using an amount of an orally dosed TLR-7 compound in an amount sufficient to increase IFN in the gastrointestinal area, including the liver, but not significantly increasing systemic IFN.
Claims27
A method of treating a gastrointestinal disorder in a human patient in need thereof, comprising administering to the patient an orally administered amount of a TLR agonist sufficient to provide modified IFN expression in the gastrointestinal area, but in an amount less than sufficient to significantly alter systemic IFN.
A kit comprising an oral dosage form pharmaceutical composition of compound B, in a package adapted for distribution of said oral dosage form pharmaceutical composition in an amount between 0.5 mg and 12 mg. once per week.
Dependencies are inferred from the claim text.