Ophthalmic compositions comprising polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymers
AssigneeAllergan, Inc.
InventorsAnuradha V. Gore, Chetan P. Pujara, Richard S. Graham, Melissa Gulmezian, Kristin Prinn, Ramakrishnan Srikumar
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Abstract
Compositions and methods related to ophthalmic use of polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymers and therapeutic uses are described herein.
Claims20
A topical ophthalmic composition comprising a polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymer.
A method of solubilizing a therapeutically active agent comprising providing a composition comprising the therapeutically active agent and a polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymer, wherein the therapeutically active agent is not completely soluble in the composition at room temperature without the polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymer.
A method of stabilizing a therapeutically active agent comprising combining the therapeutically active agent with a polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymer to thereby improve stability of the therapeutically active agent.
Dependencies are inferred from the claim text.