Compounds for stem cell differentiation

A compound of Formula I:

• or a chirally pure stereoisomer, pharmaceutically acceptable salt or solvate thereof,
• wherein:
• R1 is independently hydrogen (C1-C6)alkyl or a moiety forming a salt;
• R2 is independently hydrogen or (C1-C6)alkyl;
• R3 is independently OR8 or NR13R13′;
• R4 is independently substituted or unsubstituted aryl, heteroalkyl, heterocycloalkyl, or heteroaryl substituted or unsubstituted pyridine, wherein phenyl or pyridine is optionally independently substituted with 1 to 3 R9 substituents;
• R5, R5′, R6, R6′, R7, and R7′ are each independently hydrogen or (C1-C6)alkyl;
• R8, R13, and R13′ are each independently hydrogen, (C1-C6)alkyl, (C3-C8)cycloalkyl, substituted or unsubstituted heterocyclyl, aryl, (C1-C6)alkylaryl, or (C1-C6)alkylNR10R10′;
• each R9 is independently hydrogen, halogen, (C1-C6)alkyl, (C1-C6)alkoxy, cyclo(C1-C6)alkyl, substituted or unsubstituted phenyl, substituted or unsubstituted pyridine, substituted or unsubstituted indolyl;
• substituted or unsubstituted pyrrolidinyl, or substituted or unsubstituted piperidinyl, wherein phenyl, pyridine, indolyl, pyrrolidinyl and piperidinyl are each optionally independently substituted with hydrogen, halogen, or (C1-C6)alkyl;
• and
• R10 and R10′ are each independently hydrogen, (C1-C6)alkyl, aryl, or (C1-C6)alkylaryl.