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US 2013/0157886 A1Published application
Methods of detecting lung cancer
OwnerBernard MICHOT, Olivier DELFOUR +1inventors
InventorsBernard MICHOT, Olivier DELFOUR, David H. PERSING
Life of this patent
Estimating the term…
Abstract
Methods of lung cancer in a sample from a patient are provided. Methods of detecting changes in expression of one or more target RNAs associated with lung cancer are also provided. Compositions and kits are also provided.
Claims24
1-55. (canceled)
A method for detecting the presence of lung cancer in a subject, comprising:
- a) contacting a sample from a subject with a reagent or reagents for detecting a target RNA in a sample from the subject, wherein the target RNA:
- (i) is capable of specifically hybridizing to a nucleic acid having a sequence of SEQ ID NO:
- 260;
- or
- (ii) comprises a sequence that is complementary to at least 15 contiguous nucleotides of a sequence of SEQ ID NO:
- 260;
- or
- (iii) comprises at least 15 contiguous nucleotides of SEQ ID NO:
- 566;
- and
- b) comparing the level of the target RNA in the sample to a normal level of the target RNA;
- wherein a level of the target RNA that is greater than a normal level of the target RNA indicates the presence of lung cancer in the subject.
9 more elements
An isolated polynucleotide comprising at least 8 contiguous nucleotides of SEQ ID NO:
- 566 or the complement of SEQ ID NO:
- 566.
Dependencies are inferred from the claim text.