Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
AssigneeNaturon Pharmaceuticals, Inc.
InventorsNeal Bricker, Stewart Shankel, Christopher D. Cain, Mark Mitchnick, Michael Schmertzler
Life of this patent
Estimating the term…
Abstract
The present invention relates to diuretic pharmaceutical compositions and methods and in particular to certain derivatives of the formula I: or a prodrug or pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier.
Claims11
-24. (canceled)
An isolated antibody that specifically binds to xanthurenic acid-8-O-β-D-glucoside.
A diagnostic kit for assaying xanthurenic acid-8-O-β-D-glucoside in a serum sample, comprising one or more monoclonal antibodies directed against xanthurenic acid-8-O-β-D-glucoside.
(canceled)
A process for monitoring or detecting a disease associated with an abnormal level of xanthurenic acid-8-O-β-D-glucoside;
- the process comprising:
- a. exposing a biological sample to a monoclonal antibody directed against xanthurenic acid-8-β-D-glucoside;
- and
- b. detecting a level of xanthurenic acid-8-β-D-glucoside in said biological sample using the monoclonal antibody, wherein an elevated level of xanthurenic acid-8-O-β-D-glucoside in said biological sample is associated with the disease.
-37. (canceled)
Dependencies are inferred from the claim text.