Immuno-pet imaging of antibodies and immunoconjugates and uses therefor
AssigneeGenentech, Inc.
InventorsMark Dennis, Jan Marik, Paul Polakis, Bonnee Rubinfeld, Simon Williams
Life of this patent
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Abstract
Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of detecting or determining the presence of STEAP-1 proteins are provided.
Claims8
A method of determining the presence of a STEAP-1 protein in a biological sample suspected of containing said STEAP-1 protein, said method comprising exposing said biological sample to a 89Zirconium-labeled anti-STEAP-1 antibody and determining binding of said 89Zirconium-labeled anti-STEAP-1 antibody to said protein in said biological sample, wherein binding of said 89Zirconium-labeled anti-STEAP-1 antibody to said protein is indicative of the presence of said STEAP-1 protein in said biological sample.
A composition comprising a 89Zirconium-labeled anti-STEAP-1 antibody.
Dependencies are inferred from the claim text.