Method of reducing incidence of intraocular pressure associated with intraocular use of corticosteroids
AssigneeAlimera Sciences, Inc.
InventorKen GREEN
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Abstract
A method of treating an ocular disease in a subject using a corticosteroid with reduced incidence of intraocular pressure lowering surgery comprises injecting an intravitreal insert capable of providing a therapeutic effect for an extended period of time. The intravitreal insert delivers sustained sub-microgram levels of corticosteroid.
Claims27
A method of treating an ocular disease in a subject using a corticosteroid, wherein the incidence of TOP lowering surgery at 1 year or more after treatment is less than 10%, comprising injecting at least one free-floating intravitreal insert comprising a dosage of corticosteroid into an eye of the subject such that the intravitreal insert settles near the base of the eye, wherein the intravitreal insert is configured to release the corticosteroid in a controlled manner over a time period of at least one year.
A method of administering a corticosteroid to the eye wherein the incidence of TOP lowering surgery at 1 year or more after treatment is less than 10%, comprising injecting at least one free-floating intravitreal insert comprising a corticosteroid into an eye of a subject such that the intravitreal insert settles near the base of the eye, wherein the intravitreal insert is configured to release the corticosteroid in a controlled manner over a time period of at least one year.
A method of reducing the incidence of TOP lowering surgeries in patients receiving intraocular treatment with corticosteroids to less than 10% at 1 year or more after treatment, comprising injecting at least one free-floating intravitreal insert comprising a corticosteroid into an eye of the subject such that the intravitreal insert settles near the base of the eye, wherein the intravitreal insert is configured to release the corticosteroid in a controlled manner over a time period of at least one year.
Dependencies are inferred from the claim text.