Chlamydia trachomatis antigens
OwnerGiulio Rattiinventor
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Abstract
Proteins encoded by Chlamydia trachomatis which are immunogenic in humans as a consequence of infection have been identified using Western blots of two-dimensional electrophoretic maps. Several known immunogens were identified, as were proteins not previously known to be immunogens, and proteins not previously reported as expressed gene products.
Claims4
A method of eliciting a Chlamydia-specific immune response in a patient, the method comprises the step of administering to the patient an effective amount of an immunogenic composition selected from the group consisting of (i) an immunogenic protein comprising a Chlamydia trachomatis htrA protein having an N-terminal sequence as shown in SEQ ID NO:3;
- (ii) a nucleic acid encoding a Chlamydia trachomatis htrA protein having an N-terminal sequence as shown in SEQ ID NO:3;
- (iii) an antibody specific for a Chlamydia trachomatis htrA protein having an N-terminal sequence as shown SEQ ID NO:3;
- and (iv) combinations of (i), (ii) and (iii).
Dependencies are inferred from the claim text.