Device and method for manipulating or analysing a liquid sample
AssigneeBoehringer Ingelheim International GmbH
InventorsTobias Rodenfels, Gert Blankenstein, Dirk Osterloh
Life of this patent
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Abstract
A device and a method for manipulating or analysing a liquid sample in a microfluidic channel are proposed. In order to implement an immunoassay, a movable substrate having a binding region is inserted in the channel. The substrate is embodied as a plate-like plastic part and is microstructured in the binding region. It is magnetically movable in the channel and for optical detection can be moved into a gas space.
Claims23
A device (1) for the manipulation or analysis of a liquid sample (2), having a microfluidic channel (3) for receiving the sample (2) and having a substrate (4) that is movable in the channel (3), which comprises at least one detection or binding region (5) for a substance, the substance being or containing an analyte of the sample (2), a complex (6) formed thereby or a reaction product dependent thereon or a reagent that interacts or binds with an analyte of the sample (2), a complex (6) formed thereby or a reaction product dependent thereon,
- characterised in that
- the device (1) comprises a gas space, the substrate (4) being movable out of the sample (2) into the gas space in order to detect the substance or the substrate (4) being movable through the gas space into a liquid that is different from the sample (2) or vice versa.
-24. (canceled)
Dependencies are inferred from the claim text.