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US 2013/0155371 A1Published application
Redox processes for contact lens modification
AssigneeSemprus Biosciences Corp.
InventorsZheng ZHANG, Jun LI, Matt SKINNER, Christopher R. LOOS
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Abstract
Medical devices having a wettable, biocompatible surface are described herein. Processes for producing such devices are also described.
Claims29
A process for modifying the surface of a silicon-containing polymer, the process comprising the steps of:
- forming a reaction mixture comprising the silicon-containing polymer, a polymerization monomer, a free radical initiator system and a solvent system, the polymerization monomer comprising a zwitterionic monomer and the free radical redox initiator system comprising a peroxide in the presence of a metal ion;
- and
- polymerizing the polymerization monomer in the reaction mixture to form a surface modification polymer on the surface of the silicon-containing polymer.
A process for modifying the surface of a silicon-containing polymer, the process comprising the steps of:
- forming a reaction mixture comprising the silicon-containing polymer, a polymerization monomer, a free radical initiator system and a solvent system, the polymerization monomer comprising a zwitterionic monomer and the free radical redox initiator system comprising a persulfate;
- and
- polymerizing the polymerization monomer in the reaction mixture to form a surface modification polymer on the surface of the silicon-containing polymer.
A process for modifying the surface of a silicon-containing polymer, the process comprising the steps of:
- forming a reaction mixture comprising the silicon-containing polymer, a polymerization monomer, a free radical initiator system and a solvent system, the polymerization monomer comprising a zwitterionic monomer and the free radical redox initiator system comprising one or more of:
- (i) a peroxide and a metal salt;
- (ii) a peroxide and a reducing agent;
- (iii) an inorganic reductant and an inorganic oxidant;
- (iv) an organic/inorganic redox pair;
- (v) a monomer that is capable of acting as a component of the redox pair of item (iv);
- and (vi) a free radical initiator;
- and
- polymerizing the polymerization monomer in the reaction mixture to form a surface modification polymer on the surface of the silicon-containing polymer.
6 more elements
Dependencies are inferred from the claim text.