Adaptive cycling for respiratory treatment apparatus

A respiratory treatment apparatus for cycling synchronized respiratory pressure treatment, the apparatus comprising:

• a patient interface to direct a breathable gas;
• a flow generator coupled with the patient interface to generate the breathable gas in inspiratory and expiratory pressure cycles through the patient interface;
• a flow sensor to provide a signal indicative of flow through the patient interface;
• a processor, coupled with the flow generator and the flow sensor, the processor configured to control:
• generation of inspiratory pressure and expiratory pressure over a first plurality of cycles, wherein the setting of the expiratory pressure is based on a first cycling criteria;
• and
• generation of inspiratory pressure and expiratory pressure over a second plurality of cycles subsequent to the first plurality of cycles, wherein the setting of the expiratory pressure is based on a second cycling criteria, the second cycling criteria being different from the first cycling criteria and being initiated for operation subsequent to the first plurality of cycles.

An automated processing method for cycling a respiratory treatment apparatus that controls a delivery of a synchronized respiratory treatment, the method comprising:

• determining a first flow measure with a flow sensor;
• determining a second flow measure attributable to the respiratory treatment apparatus;
• and
• evaluating, with a processor, a cycling criteria as a function of the first flow measure and the second flow measure.

A respiratory treatment apparatus for cycling synchronized respiratory pressure treatment, the apparatus comprising:

• a patient interface to direct a breathable gas;
• a flow generator coupled with the patient interface to generate the breathable gas in inspiratory and expiratory pressure cycles through the patient interface;
• a flow sensor to provide a signal indicative of patient flow through the patient interface;
• a processor, coupled with the flow generator and the flow sensor, the processor configured to control:
• a determination of a first flow measure from the flow sensor;
• a determination of a second flow measure attributable to the respiratory treatment apparatus;
• and
• an evaluation of a cycling criteria as a function of the first flow measure and the second flow measure.

An automated processing method to determine a signal indicative of patient respiration for synchronization of a respiratory treatment apparatus, the method comprising:

• determining a first inspiratory flow measure with a flow sensor;
• determining a second inspiratory flow measure;
• and
• determining, with a processor, a patient respiration measure as a function of the first inspiratory flow measure, the second inspiratory flow measure and an estimate of resistance and compliance derived from an expiratory portion of a flow measure of the flow sensor, the patient respiratory measure representing patient respiratory muscles effort;
• and
• determining a timing for switching a pressure treatment based on the respiration measure.

A monitoring apparatus to determine a signal indicative of patient respiration for synchronization of a respiratory treatment, the apparatus comprising:

• a controller having at least one processor to access data representing a measured flow of breathable gas from a flow sensor, the controller being further configured to:
• determine a first inspiratory flow measure with the data;
• determine a second inspiratory flow measure;
• and
• determine a patient respiration signal as a function of the first inspiratory flow measure, the second inspiratory flow measure and an estimate of resistance and compliance derived from an expiratory portion of a flow measure of the flow sensor, the patient respiratory signal representing effort attributable to patient respiratory muscles;
• and
• determine a timing for switching a pressure treatment based on the respiration measure.

An automated processing method for cycling a respiratory treatment apparatus that controls a delivery of a synchronized respiratory treatment, the method comprising:

• determining a flow measure with a flow sensor;
• determining a pressure measure with a pressure sensor;
• determining, with a processor, an estimate of muscle effort as a function of the flow measure and pressure measure;
• and
• deriving, with the processor, a cycling control signal as a function of the estimate of muscle effort.

A respiratory treatment apparatus for cycling synchronized respiratory pressure treatment, the apparatus comprising:

• a patient interface to direct a breathable gas;
• a flow generator coupled with the patient interface to generate the breathable gas in inspiratory and expiratory pressure cycles through the patient interface;
• a flow sensor to provide a signal indicative of patient flow through the patient interface;
• a pressure sensor to provide a signal indicative of pressure at the patient interface;
• a processor, coupled with the flow generator, the pressure sensor and the flow sensor, the processor configured to control:
• a determination of a flow measure with the flow sensor;
• a determination of a pressure measure with the pressure sensor;
• a determination of an estimate of muscle effort as a function of the flow measure and pressure measure;
• and
• a derivation of a cycling control signal as a function of the estimate of muscle effort.

A respiratory treatment apparatus for switching synchronized respiratory pressure treatment, the apparatus comprising:

• a patient interface to direct a breathable gas;
• a flow generator coupled with the patient interface to generate the breathable gas in inspiratory and expiratory pressure cycles through the patient interface;
• an electro-optical sensor for non-invasively measuring diaphragmatic muscle activity;
• and
• a processor, coupled with the flow generator and the sensor, the processor configured to control:
• a determination of muscle effort signal with the sensor;
• and
• a derivation of a switching control signal as a function of the muscle effort signal.