Certain chemical entities, compositions and methods

A compound of Formula V:

• or a pharmaceutically acceptable salt thereof, wherein
• R2 is selected from hydrogen and lower alkyl;
• R3 is selected from lower alkyl substituted with hydroxy and lower alkyl substituted with optionally substituted amino;
• R11 is selected from hydrogen, cyano, nitro and halo;
• R12 is optionally substituted lower alkoxy;
• R13 is hydrogen;
• R14 is 1H-imidazol-4-yl substituted with one, two or three groups selected from optionally substituted lower alkyl, halo, acyl, sulfonyl, cyano, nitro, optionally substituted amino, and optionally substituted heteroaryl;
• R15 is selected from hydrogen, halo, hydroxy, and lower alkyl.