Compounds and methods for modulating g protein-coupled receptors

A compound of Formula (I):

• wherein:
• n is selected from 0, 1, 2, 3 and 4;
• A is selected from:
• A is:
• R8 is selected from H, C1-4alkyl and phenyl optionally substituted with 1 to 3 radicals independently selected from halo, C1-4alkyl, halo-substitued-C1-4alkyl, C1-4alkoxy and halo-substituted-C1-4alkoxy;
• R1 is selected from —COOH, —SO3H and tetrazolyl;
• R2 is selected from halo, C1-4alkyl, halo-substitued-C1-4alkyl, C1-4alkoxy and halo-substituted-C1-4alkoxy;
• R3, R4, R5, R6 or R7 are independently selected from H, cyano, hydroxyl, nitro, halo, C1-4alkyl, halo-substitued-C1-4alkyl, C1-4alkoxy, halo-substituted-C1-4alkoxy, X2OR11, —X2NR12R13, —X2R11, —X2OX3R11 and —X2OX3OR11;
• wherein X2 is selected from a bond and C1-4alkylene;
• X3 is C1-4alkylene;
• R11 is selected from C1-6alkyl, heteroaryl and aryl, each optionally substituted with 1 to 3 radicals independently selected from halo, cyano, hydroxyl, nitro, amino, C1-4alkyl, halo-substitued-C1-4alkyl, C1-4alkoxy and halo-substituted-C1-4alkoxy;
• R12 and R13 are independently selected from H and C1-6alkyl;
• or
• R3 and R4 or R5 and R6 are each independently C1-4alkyl and taken together with the carbon atoms to which they are attached can form a phenyl ring;
• wherein said phenyl of the combination of R3 and R4 or R5 and R6 is optionally substituted with 1 to 3 radicals independently selected from cyano, amino, hydroxyl, nitro, halo, C1-4alkyl, halo-substitued-C1-4alkyl, C1-4alkoxy and halo-substituted-C1-4alkoxy;
• or the pharmaceutically acceptable salts thereof.